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SELECT Trial (Semaglutide)# The SELECT trial (Lincoff et al., NEJM 2023) enrolled 17,604 adults aged 45 or older with overweight or obesity and established cardiovascular disease, but without diabetes

As the evidence evolves, our practice should evolve with it

In the U.S., tesamorelin is sold under the brand name Egrifta and is used to treat HIV-positive patients with lipodystrophy caused by long-term antiretroviral therapy (ART)

Zepbound costs begin at $299 monthly, offering flexibility for various financial situations

-mild leukocytosis due to an increase in the number of neutrophils (not considered clinically significant)

Also keep in mind that weight-management GLP-1s are most effective when paired with lifestyle changes such as eating healthy foods, exercising, practicing good sleep hygiene, and keeping stress levels low